He can\'t even run his mouth without someone else writing the words and using a teleprompter. What made him think he could run a country as complex as the United States? OH!! But he is running it, right into the ground!!

I think that Obama's greatest mistake has been healthcare. Putting aside all the potential problems of having a public option, I think that America has some larger problems. The two wars, the economy, and climate change all need to be addressed. Why is Obama devoting billions of dollars and most of his political capital to providing what will be mediocre healthcare for 10-15% of the population, when all Americans have an interest in halting global warming, in recovering economic prosperity, and in winning the wars in Iraq and Afghanistan? If I were Obama, I would spend the first two years in office entirely on ensuring a safe economic recovery and putting Afghanistan back together. Once those are out of the way, when an improved economy has made Americans less desperate, it will be possible to examine healthcare and climate change more closely and find solutions to their improvement.

hmm... I don't think Obama has made huge mistakes yet.
Although Republicans are trying to make him look worse than Hitler at times and many incorrect stories have been published... the Obama team haven't reacted strongly against all this rumor mongering. I think that's Obama's biggest mistake actually... On the other hand it speaks for Obama that he hasn't lowered himself to (some) republican politicians.